The oil and gas sector is a leading source of emissions that are harmful to public health, the environment, and the climate. Pollutants including methane, volatile organic compounds, and carbon dioxide occur throughout a vast infrastructure network that connects production wells to electricity generation, urban centers, and household appliances. Our work on oil and gas provides scientific analyses and expertise in environmental science, public health, engineering, and air quality modeling. We collaborate with leading national and international research institutions and advise state and federal decision makers on the development of effective science-based solutions.